

Non-invasive tests used to stage liver fibrosis in metabolic dysfunction-associated steatohepatitis play a growing role in care and trial recruitment, but their performance in routine practice may differ from results seen in clinical studies.

Non-invasive tests used to stage liver fibrosis in metabolic dysfunction-associated steatohepatitis play a growing role in care and trial recruitment, but their performance in routine practice may differ from results seen in clinical studies.
Of course the tests look great in trials. Trials pick clean patients, tidy biopsies and specialists who know exactly what they’re doing. Then the same blood panels and elastography machines get shoved into a overworked primary care clinic in Ohio, and suddenly the numbers fall apart. Shocking. Nobody saw that coming except everyone who has ever set foot in a real clinic.